BindingDB PrimarySearch

Found 24 hits of ic50 for monomerid = 50300027
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Her1 by fluorescence polarization assay				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Her2 by fluorescence polarization assay				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Src				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Ret				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Abl1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Her4				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of FGFR2				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Flt4				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of PKCalpha				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of MAPK1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Flt1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Raf1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Flt3				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Aurora B				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of IGF1R				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Kit				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of FGFR1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Met				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of Akt1				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of CDK2				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50300027 ((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hanmi Research Center Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				J Med Chem 52: 6880-8 (2009) Article DOI: 10.1021/jm901146p BindingDB Entry DOI: 10.7270/Q28W3DDJ
Hanmi Research Center Curated by ChEMBL					More data for this Ligand-Target Pair