BindingDB PrimarySearch

Found 2 hits of ic50 for monomerid = 50315089
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Rattus norvegicus)	BDBM50315089 ((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of rat brain mTOR assessed as p70S6k-GST protein phosphorylation after 30 mins by ELISA				Bioorg Med Chem Lett 20: 2654-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.029 BindingDB Entry DOI: 10.7270/Q2959HQ5
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50315089 ((R)-1-(4-(4-(3-methylmorpholino)-6-(tetrahydro-2H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha assessed as PIP3 accumulation after 24 mins by HTRF assay				Bioorg Med Chem Lett 20: 2654-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.029 BindingDB Entry DOI: 10.7270/Q2959HQ5
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair