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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50326185   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50326185
PNG
((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-3-...)
Show SMILES COc1ccc-2c(c1)\C(=N/OCCCN(C)C)c1c-2cnc2ccccc12
Show InChI InChI=1S/C22H23N3O2/c1-25(2)11-6-12-27-24-22-18-13-15(26-3)9-10-16(18)19-14-23-20-8-5-4-7-17(20)21(19)22/h4-5,7-10,13-14H,6,11-12H2,1-3H3/b24-22+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis

J Med Chem 53: 6164-79 (2010)


Article DOI: 10.1021/jm1005447
BindingDB Entry DOI: 10.7270/Q2BZ6710
More data for this
Ligand-Target Pair