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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50326187   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50326187
PNG
((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-2-...)
Show SMILES COc1ccc-2c(c1)\C(=N/OCCN(C)C)c1c-2cnc2ccccc12
Show InChI InChI=1S/C21H21N3O2/c1-24(2)10-11-26-23-21-17-12-14(25-3)8-9-15(17)18-13-22-19-7-5-4-6-16(19)20(18)21/h4-9,12-13H,10-11H2,1-3H3/b23-21+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis

J Med Chem 53: 6164-79 (2010)


Article DOI: 10.1021/jm1005447
BindingDB Entry DOI: 10.7270/Q2BZ6710
More data for this
Ligand-Target Pair