Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50326193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50326193 ((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...) Show SMILES COc1ccc-2c(c1)\C(=N/OCCN1CCCC1)c1c-2c(nc2ccccc12)N1CCNCC1 Show InChI InChI=1S/C27H31N5O2/c1-33-19-8-9-20-22(18-19)26(30-34-17-16-31-12-4-5-13-31)24-21-6-2-3-7-23(21)29-27(25(20)24)32-14-10-28-11-15-32/h2-3,6-9,18,28H,4-5,10-17H2,1H3/b30-26+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis				J Med Chem 53: 6164-79 (2010) Article DOI: 10.1021/jm1005447 BindingDB Entry DOI: 10.7270/Q2BZ6710
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