Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50327148 ((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Mylan School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cells | Bioorg Med Chem 19: 504-12 (2011) Article DOI: 10.1016/j.bmc.2010.11.002 BindingDB Entry DOI: 10.7270/Q29Z9567 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50327148 ((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology Curated by ChEMBL | Assay Description Displacement of [3H]WIN 35428 from Sprague-Dawley rat striatal tissue after 2 hrs by liquid scintillation counting | Bioorg Med Chem 18: 7221-38 (2010) Article DOI: 10.1016/j.bmc.2010.08.034 BindingDB Entry DOI: 10.7270/Q24F1QZZ | |||||||||||
More data for this Ligand-Target Pair |