Compile Data Set for Download or QSAR

Found 5 hits of ic50 for monomerid = 50330932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of voltage-gated Na channel 1.8 (unknown origin)				J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat))	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Mus musculus)	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330932 (CHEMBL1276882 | N-((2-Morpholin-4-yl-pyridin-3-yl)...) Show SMILES FC(F)(F)Oc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1N1CCOCC1 Show InChI InChI=1S/C22H20F3N5O3/c23-22(24,25)33-17-5-3-15(4-6-17)18-13-26-14-19(29-18)21(31)28-12-16-2-1-7-27-20(16)30-8-10-32-11-9-30/h1-7,13-14H,8-12H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.2 by electrophysiology				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair