Found 2 hits of ic50 for monomerid = 50351602 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50351602
(CHEMBL1822791)Show SMILES CN(C)CCNC(=O)c1cc2NC(=O)C(=NNC(=O)Cc3ccc4OCCc4c3)c2c(Br)c1 |w:15.15| Show InChI InChI=1S/C23H24BrN5O4/c1-29(2)7-6-25-22(31)15-11-16(24)20-17(12-15)26-23(32)21(20)28-27-19(30)10-13-3-4-18-14(9-13)5-8-33-18/h3-4,9,11-12H,5-8,10H2,1-2H3,(H,25,31)(H,27,30)(H,26,28,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of human c-MET |
Eur J Med Chem 46: 3675-80 (2011)
Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50351602
(CHEMBL1822791)Show SMILES CN(C)CCNC(=O)c1cc2NC(=O)C(=NNC(=O)Cc3ccc4OCCc4c3)c2c(Br)c1 |w:15.15| Show InChI InChI=1S/C23H24BrN5O4/c1-29(2)7-6-25-22(31)15-11-16(24)20-17(12-15)26-23(32)21(20)28-27-19(30)10-13-3-4-18-14(9-13)5-8-33-18/h3-4,9,11-12H,5-8,10H2,1-2H3,(H,25,31)(H,27,30)(H,26,28,32) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of human c-MET |
Eur J Med Chem 46: 3675-80 (2011)
Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676 |
More data for this Ligand-Target Pair | |