Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50351952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50351952 (CHEMBL1822057) Show SMILES CC(=O)Nc1cn2cc(ccc2n1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C20H15ClFN5O3S/c1-12(28)24-18-11-27-10-13(2-7-19(27)25-18)14-8-17(20(21)23-9-14)26-31(29,30)16-5-3-15(22)4-6-16/h2-11,26H,1H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged mTOR-mediated 4E-BP1 phosphorylation after 60 mins by TR-FRET assay				J Med Chem 54: 5174-84 (2011) Article DOI: 10.1021/jm2004442 BindingDB Entry DOI: 10.7270/Q2V12567
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50351952 (CHEMBL1822057) Show SMILES CC(=O)Nc1cn2cc(ccc2n1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2)c1 Show InChI InChI=1S/C20H15ClFN5O3S/c1-12(28)24-18-11-27-10-13(2-7-19(27)25-18)14-8-17(20(21)23-9-14)26-31(29,30)16-5-3-15(22)4-6-16/h2-11,26H,1H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3K-mediated Akt phosphorylation at Ser 473 in human U87MG cells after 2 hrs by alphascreen assay				J Med Chem 54: 5174-84 (2011) Article DOI: 10.1021/jm2004442 BindingDB Entry DOI: 10.7270/Q2V12567
					More data for this Ligand-Target Pair