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Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50364291   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))
BDBM50364291
PNG
(CHEMBL1952304)
Show SMILES CCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1
Show InChI InChI=1S/C19H31BO2/c1-6-7-8-9-10-11-16-12-14-17(15-13-16)20-21-18(2,3)19(4,5)22-20/h12-15H,6-11H2,1-5H3
KEGG

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PC cid
PC sid
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Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...


Bioorg Med Chem Lett 22: 1397-401 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.043
BindingDB Entry DOI: 10.7270/Q28G8M5N
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50364291
PNG
(CHEMBL1952304)
Show SMILES CCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1
Show InChI InChI=1S/C19H31BO2/c1-6-7-8-9-10-11-16-12-14-17(15-13-16)20-21-18(2,3)19(4,5)22-20/h12-15H,6-11H2,1-5H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay


Bioorg Med Chem Lett 22: 1397-401 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.043
BindingDB Entry DOI: 10.7270/Q28G8M5N
More data for this
Ligand-Target Pair
Lipoprotein lipase


(Homo sapiens (Human))
BDBM50364291
PNG
(CHEMBL1952304)
Show SMILES CCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1
Show InChI InChI=1S/C19H31BO2/c1-6-7-8-9-10-11-16-12-14-17(15-13-16)20-21-18(2,3)19(4,5)22-20/h12-15H,6-11H2,1-5H3
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UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...


Bioorg Med Chem Lett 22: 1397-401 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.043
BindingDB Entry DOI: 10.7270/Q28G8M5N
More data for this
Ligand-Target Pair
Lipoprotein lipase


(Homo sapiens (Human))
BDBM50364291
PNG
(CHEMBL1952304)
Show SMILES CCCCCCCc1ccc(cc1)B1OC(C)(C)C(C)(C)O1
Show InChI InChI=1S/C19H31BO2/c1-6-7-8-9-10-11-16-12-14-17(15-13-16)20-21-18(2,3)19(4,5)22-20/h12-15H,6-11H2,1-5H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.50E+4n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay


Bioorg Med Chem Lett 22: 1397-401 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.043
BindingDB Entry DOI: 10.7270/Q28G8M5N
More data for this
Ligand-Target Pair