BindingDB PrimarySearch

Found 2 hits of ic50 for monomerid = 50378458
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50378458 (LYONISIDE) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University Curated by ChEMBL					Assay Description Inhibition of PDE4D2 catalytic domain (86 to 413 residues) (unknown origin) using [3H]-cAMP as substrate after 15 mins by liquid scintillation counti...				Eur J Med Chem 114: 134-40 (2016) Article DOI: 10.1016/j.ejmech.2015.12.002 BindingDB Entry DOI: 10.7270/Q2765H8J
Sun Yat-Sen University Curated by ChEMBL					More data for this Ligand-Target Pair
Transcription factor HES-1 (Mus musculus)	BDBM50378458 (LYONISIDE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assay				Bioorg Med Chem Lett 19: 5778-81 (2009) Article DOI: 10.1016/j.bmcl.2009.07.146 BindingDB Entry DOI: 10.7270/Q26Q1Z5X
Chiba University Curated by ChEMBL					More data for this Ligand-Target Pair