Found 3 hits of ic50 for monomerid = 50379495 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50379495
(CHEMBL2012407)Show SMILES Cn1cc(Nc2ncc3cnn([C@H]4C[C@@H]5C[C@@H]5C4)c3n2)cc1C(=O)N1CCCC1 |r| Show InChI InChI=1S/C21H25N7O/c1-26-12-16(9-18(26)20(29)27-4-2-3-5-27)24-21-22-10-15-11-23-28(19(15)25-21)17-7-13-6-14(13)8-17/h9-14,17H,2-8H2,1H3,(H,22,24,25)/t13-,14+,17- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora A kinase |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50379495
(CHEMBL2012407)Show SMILES Cn1cc(Nc2ncc3cnn([C@H]4C[C@@H]5C[C@@H]5C4)c3n2)cc1C(=O)N1CCCC1 |r| Show InChI InChI=1S/C21H25N7O/c1-26-12-16(9-18(26)20(29)27-4-2-3-5-27)24-21-22-10-15-11-23-28(19(15)25-21)17-7-13-6-14(13)8-17/h9-14,17H,2-8H2,1H3,(H,22,24,25)/t13-,14+,17- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of aurora B kinase |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50379495
(CHEMBL2012407)Show SMILES Cn1cc(Nc2ncc3cnn([C@H]4C[C@@H]5C[C@@H]5C4)c3n2)cc1C(=O)N1CCCC1 |r| Show InChI InChI=1S/C21H25N7O/c1-26-12-16(9-18(26)20(29)27-4-2-3-5-27)24-21-22-10-15-11-23-28(19(15)25-21)17-7-13-6-14(13)8-17/h9-14,17H,2-8H2,1H3,(H,22,24,25)/t13-,14+,17- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc.
Curated by ChEMBL
| Assay Description Inhibition of CDK1 |
Bioorg Med Chem Lett 22: 2070-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.019 BindingDB Entry DOI: 10.7270/Q2833T1N |
More data for this Ligand-Target Pair | |