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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50386293   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM50386293
PNG
(CHEMBL2049100)
Show SMILES N[C@H]1Cc2c(cccc2C(F)(F)F)N(O)C1=O |r|
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-2-1-3-8-5(6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


ACS Med Chem Lett 3: 187-192 (2012)


Article DOI: 10.1021/ml200204m
BindingDB Entry DOI: 10.7270/Q2MC9135
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Rattus norvegicus)
BDBM50386293
PNG
(CHEMBL2049100)
Show SMILES N[C@H]1Cc2c(cccc2C(F)(F)F)N(O)C1=O |r|
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-2-1-3-8-5(6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


ACS Med Chem Lett 3: 187-192 (2012)


Article DOI: 10.1021/ml200204m
BindingDB Entry DOI: 10.7270/Q2MC9135
More data for this
Ligand-Target Pair