Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM50390999 (CEFOPERAZONE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.87E+4 | n/a | 4.84E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ondokuz Mayis University | Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-... | J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 6 (Rattus norvegicus) | BDBM50390999 (CEFOPERAZONE) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.98E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes | Drug Metab Pharmacokinet 17: 125-9 (2002) Article DOI: 10.2133/dmpk.17.125 BindingDB Entry DOI: 10.7270/Q2VT1VZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione peroxidase 1 (Homo sapiens (Human)) | BDBM50390999 (CEFOPERAZONE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.45E+5 | n/a | 3.13E+5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Ondokuz Mayis University | Assay Description Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ... | J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microsomal glutathione S-transferase 1 (Homo sapiens (Human)) | BDBM50390999 (CEFOPERAZONE) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.67E+5 | n/a | 4.84E+5 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Ondokuz Mayis University | Assay Description Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,... | J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 7 (Homo sapiens (Human)) | BDBM50390999 (CEFOPERAZONE) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells | Eur J Pharmacol 465: 1-7 (2003) BindingDB Entry DOI: 10.7270/Q2CC11SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 7 (Rattus norvegicus) | BDBM50390999 (CEFOPERAZONE) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.62E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells | Eur J Pharmacol 465: 1-7 (2003) BindingDB Entry DOI: 10.7270/Q2CC11SX | |||||||||||
More data for this Ligand-Target Pair |