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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50398806   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A


(Homo sapiens (Human))		BDBM50398806
PNG
(CHEMBL2180075)
Show SMILES CC(N1CC(C1)Oc1cc(F)ccc1F)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C21H23F2N5O3/c1-12(27-10-15(11-27)31-18-8-13(22)2-3-17(18)23)19-25-20-16(21(29)26-19)9-24-28(20)14-4-6-30-7-5-14/h2-3,8-9,12,14-15H,4-7,10-11H2,1H3,(H,25,26,29)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 57n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay

J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair