Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50403064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403064 (CHEMBL2216881) Show SMILES CN(C)CC(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1 |r,wU:7.6,wD:10.13,(15.91,-32.01,;14.57,-32.78,;14.57,-34.32,;13.24,-32.01,;11.91,-32.77,;11.91,-34.31,;10.57,-32,;9.24,-32.77,;9.24,-34.31,;7.91,-35.08,;6.57,-34.32,;6.57,-32.77,;7.9,-32,;5.24,-35.09,;5.25,-36.63,;3.92,-37.4,;3.92,-38.95,;5.25,-39.72,;6.59,-38.95,;6.58,-37.4,;7.92,-39.72,;8.09,-41.25,;9.59,-41.57,;10.36,-40.24,;11.86,-39.92,;12.33,-38.46,;11.3,-37.31,;9.8,-37.63,;9.33,-39.09,;6.94,-42.28,;5.48,-41.81,;7.27,-43.79,;2.58,-39.72,;1.25,-38.94,;-.09,-39.71,;-.1,-41.25,;1.24,-42.02,;2.59,-41.26,)| Show InChI InChI=1S/C25H33F2N9O2/c1-34(2)15-20(37)28-16-7-9-17(10-8-16)29-23-31-24(35-11-13-38-14-12-35)33-25(32-23)36-19-6-4-3-5-18(19)30-22(36)21(26)27/h3-6,16-17,21H,7-15H2,1-2H3,(H,28,37)(H,29,31,32,33)/t16-,17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta in human B-cells assessed as inhibition of anti-IgM-induced thymidine incorporation by radiometry				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403064 (CHEMBL2216881) Show SMILES CN(C)CC(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1 |r,wU:7.6,wD:10.13,(15.91,-32.01,;14.57,-32.78,;14.57,-34.32,;13.24,-32.01,;11.91,-32.77,;11.91,-34.31,;10.57,-32,;9.24,-32.77,;9.24,-34.31,;7.91,-35.08,;6.57,-34.32,;6.57,-32.77,;7.9,-32,;5.24,-35.09,;5.25,-36.63,;3.92,-37.4,;3.92,-38.95,;5.25,-39.72,;6.59,-38.95,;6.58,-37.4,;7.92,-39.72,;8.09,-41.25,;9.59,-41.57,;10.36,-40.24,;11.86,-39.92,;12.33,-38.46,;11.3,-37.31,;9.8,-37.63,;9.33,-39.09,;6.94,-42.28,;5.48,-41.81,;7.27,-43.79,;2.58,-39.72,;1.25,-38.94,;-.09,-39.71,;-.1,-41.25,;1.24,-42.02,;2.59,-41.26,)| Show InChI InChI=1S/C25H33F2N9O2/c1-34(2)15-20(37)28-16-7-9-17(10-8-16)29-23-31-24(35-11-13-38-14-12-35)33-25(32-23)36-19-6-4-3-5-18(19)30-22(36)21(26)27/h3-6,16-17,21H,7-15H2,1-2H3,(H,28,37)(H,29,31,32,33)/t16-,17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair