Found 2 hits of ic50 for monomerid = 50403251 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neprilysin
(Homo sapiens (Human)) | BDBM50403251
(CHEMBL299441)Show SMILES OC(=O)CCN1c2ccccc2SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O Show InChI InChI=1S/C21H22N2O4S2/c24-19(25)10-11-23-16-8-4-5-9-18(16)29-13-15(21(23)27)22-20(26)17(28)12-14-6-2-1-3-7-14/h1-9,15,17,28H,10-13H2,(H,22,26)(H,24,25)/t15-,17-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested in vitro for inhibition of neutral endopeptidase (NEP) |
Bioorg Med Chem Lett 4: 1789-1794 (1994)
Article DOI: 10.1016/S0960-894X(01)80372-3 BindingDB Entry DOI: 10.7270/Q22Z16PQ |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50403251
(CHEMBL299441)Show SMILES OC(=O)CCN1c2ccccc2SC[C@H](NC(=O)[C@@H](S)Cc2ccccc2)C1=O Show InChI InChI=1S/C21H22N2O4S2/c24-19(25)10-11-23-16-8-4-5-9-18(16)29-13-15(21(23)27)22-20(26)17(28)12-14-6-2-1-3-7-14/h1-9,15,17,28H,10-13H2,(H,22,26)(H,24,25)/t15-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested in vitro for inhibition of Angiotensin converting enzyme (ACE) |
Bioorg Med Chem Lett 4: 1789-1794 (1994)
Article DOI: 10.1016/S0960-894X(01)80372-3 BindingDB Entry DOI: 10.7270/Q22Z16PQ |
More data for this Ligand-Target Pair | |