Found 4 hits of ic50 for monomerid = 50420514 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50420514
(CHEMBL2086522)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C17H21N3O4S/c1-2-16(21)18-14-5-7-15(8-6-14)25(23,24)20-11-9-19(10-12-20)17(22)13-3-4-13/h2,5-8,13H,1,3-4,9-12H2,(H,18,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant TG2 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y
BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this
Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50420514
(CHEMBL2086522)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C17H21N3O4S/c1-2-16(21)18-14-5-7-15(8-6-14)25(23,24)20-11-9-19(10-12-20)17(22)13-3-4-13/h2,5-8,13H,1,3-4,9-12H2,(H,18,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of thrombin activated human F13a by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y
BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this
Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase K
(Homo sapiens (Human)) | BDBM50420514
(CHEMBL2086522)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C17H21N3O4S/c1-2-16(21)18-14-5-7-15(8-6-14)25(23,24)20-11-9-19(10-12-20)17(22)13-3-4-13/h2,5-8,13H,1,3-4,9-12H2,(H,18,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant TG1 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y
BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this
Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase E
(Homo sapiens (Human)) | BDBM50420514
(CHEMBL2086522)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C17H21N3O4S/c1-2-16(21)18-14-5-7-15(8-6-14)25(23,24)20-11-9-19(10-12-20)17(22)13-3-4-13/h2,5-8,13H,1,3-4,9-12H2,(H,18,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of thrombin activated human TG3 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y
BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this
Ligand-Target Pair | |
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