Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM50433276 (CHEMBL2376316) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b... | Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50433276 (CHEMBL2376316) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liqu... | Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM50433276 (CHEMBL2376316) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant DGAT2 using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liquid scintillation counti... | Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA wax alcohol acyltransferase 1 (Homo sapiens (Human)) | BDBM50433276 (CHEMBL2376316) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant AWAT1 expressed in insect cell membrane using palmitoleyl alcohol and [14C]stearoyl coenzyme A as substrate after 10 ... | Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA wax alcohol acyltransferase 2 (Homo sapiens (Human)) | BDBM50433276 (CHEMBL2376316) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant AWAT2 expressed in insect cell membrane using cetyl alcohol and [14C]oleoyl coenzyme A as substrate after 10 to 15 mi... | Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM | |||||||||||
More data for this Ligand-Target Pair |