Found 2 hits of ic50 for monomerid = 50437986 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437986
(CHEMBL2409103)Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCC2)c1 Show InChI InChI=1S/C21H19F3N4O/c22-21(23,24)15-8-5-9-16(12-15)25-20(29)26-19-13-18(14-6-4-7-14)27-28(19)17-10-2-1-3-11-17/h1-3,5,8-14H,4,6-7H2,(H2,25,26,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Inhibition of GIRK1/4 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437986
(CHEMBL2409103)Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCC2)c1 Show InChI InChI=1S/C21H19F3N4O/c22-21(23,24)15-8-5-9-16(12-15)25-20(29)26-19-13-18(14-6-4-7-14)27-28(19)17-10-2-1-3-11-17/h1-3,5,8-14H,4,6-7H2,(H2,25,26,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Inhibition of GIRK1/2 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |