Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (Homo sapiens (Human)) | BDBM50444138 (CHEMBL3093392) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ... | Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelial lipase (Homo sapiens (Human)) | BDBM50444138 (CHEMBL3093392) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by... | Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelial lipase (Homo sapiens (Human)) | BDBM50444138 (CHEMBL3093392) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of full length human endothelial lipase transfected in HEK293 cells using PED-A1 as substrate preincubated for 30 mins followed by substra... | Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatic triacylglycerol lipase (Homo sapiens (Human)) | BDBM50444138 (CHEMBL3093392) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL... | Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoprotein lipase (Homo sapiens (Human)) | BDBM50444138 (CHEMBL3093392) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Xenon Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by... | Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8 | |||||||||||
More data for this Ligand-Target Pair |