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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50448493   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA (cytosine-5)-methyltransferase 1


(Homo sapiens (Human))		BDBM50448493
PNG
(CHEMBL3126648)
Show SMILES Cc1cc(Nc2ccc(NC(=O)c3ccccc3Nc3ccnc4ccccc34)cc2)nc(N)n1
Show InChI InChI=1S/C27H23N7O/c1-17-16-25(34-27(28)30-17)31-18-10-12-19(13-11-18)32-26(35)21-7-3-5-9-23(21)33-24-14-15-29-22-8-4-2-6-20(22)24/h2-16H,1H3,(H,29,33)(H,32,35)(H3,28,30,31,34)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.23E+4n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal 600 residues-deleted DNMT1 using poly(dI-dC) as substrate in presence of AdoMet

J Med Chem 57: 701-13 (2014)


Article DOI: 10.1021/jm4012627
BindingDB Entry DOI: 10.7270/Q2028T1Q
More data for this
Ligand-Target Pair