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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM71062 (US9546164, 207 | US9694002, 207) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer... | US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha (Homo sapiens (Human)) | BDBM71062 (US9546164, 207 | US9694002, 207) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc... | US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
