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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 8055   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))
BDBM8055
PNG
(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 26 | 4...)
Show SMILES Cc1nc(N)sc1-c1ccnc(Nc2ccc(O)cc2)n1
Show InChI InChI=1S/C14H13N5OS/c1-8-12(21-13(15)17-8)11-6-7-16-14(19-11)18-9-2-4-10(20)5-3-9/h2-7,20H,1H3,(H2,15,17)(H,16,18,19)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/a7.520



University of Cambridge



Assay Description
D. melanogaster Polo kinase assays were performed as previously described40, using baculovirus-expressed Polo kinase. Enzyme was immunoprecipitated u...


Nat Chem Biol 2: 608-17 (2006)


Article DOI: 10.1038/nchembio825
BindingDB Entry DOI: 10.7270/Q29C6VS4
More data for this
Ligand-Target Pair