BindingDB PrimarySearch

Found 8 hits of ic50 for monomerid = 81993
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes				J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranes				J Med Chem 27: 1607-13 (1984) BindingDB Entry DOI: 10.7270/Q2SJ1NT8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	514	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Alpha-2 adrenergic receptor activity assessed in vitro for displacement of [3H]clonidine from specific binding sites on rat striatal membranes				J Med Chem 27: 1607-13 (1984) BindingDB Entry DOI: 10.7270/Q2SJ1NT8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A/Alpha-2A adrenergic receptor (CALF-BOVINE)	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	514	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortex				J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Eur J Med Chem 44: 2913-22 (2009) Article DOI: 10.1016/j.ejmech.2008.12.004 BindingDB Entry DOI: 10.7270/Q2NC6174
Jadavpur University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nonstructural protein 3 (Zika virus)	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged Zika virus NS2B (49 to 95 residues) - NS3 (1 to 170 residues) protease domain expressed in Escherichia coli Bl21...				Eur J Med Chem 180: 536-545 (2019) Article DOI: 10.1016/j.ejmech.2019.07.007 BindingDB Entry DOI: 10.7270/Q25D8W94
University of Patras Curated by ChEMBL					More data for this Ligand-Target Pair
Nonstructural protein 3 (Zika virus)	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Inhibition of Zika virus NS2B-NS3 protease				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126965 BindingDB Entry DOI: 10.7270/Q27M0CGT
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM81993 (BROMOCRIPTINE \| Bromocriptine+ (GTP+) \| Bromocript...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assay				Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9
TBA					More data for this Ligand-Target Pair