Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type/Kappa-type/Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM82427 (CAS_5985-38-6 | LEVORPHANOL-tartarate) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation counting | J Med Chem 21: 600-6 (1978) Article DOI: 10.1021/jm00205a003 BindingDB Entry DOI: 10.7270/Q2WM1HDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type/Kappa-type/Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM82427 (CAS_5985-38-6 | LEVORPHANOL-tartarate) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation counting | J Med Chem 21: 600-6 (1978) Article DOI: 10.1021/jm00205a003 BindingDB Entry DOI: 10.7270/Q2WM1HDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rattus norvegicus (rat)-RAT) | BDBM82427 (CAS_5985-38-6 | LEVORPHANOL-tartarate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Creighton University Curated by ChEMBL | Assay Description Concentration that produces 50% inhibition of stereospecific [3H]naloxone binding to opioid receptors in rat brain in absence of sodium. | J Med Chem 33: 245-8 (1990) BindingDB Entry DOI: 10.7270/Q2H997FH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rattus norvegicus (rat)-RAT) | BDBM82427 (CAS_5985-38-6 | LEVORPHANOL-tartarate) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Creighton University Curated by ChEMBL | Assay Description Concentration that produces 50% inhibition of stereospecific [3H]naloxone binding to opioid receptors in rat brain in presence of sodium. | J Med Chem 33: 245-8 (1990) BindingDB Entry DOI: 10.7270/Q2H997FH | |||||||||||
More data for this Ligand-Target Pair |