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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM98036 (US8486953, 19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Boehringer Ingelheim International GmbH US Patent | Assay Description Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The... | US Patent US8853193 (2014) BindingDB Entry DOI: 10.7270/Q2GX4983 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM98036 (US8486953, 19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description In vitro kinase assay using human Mnk1 and Mnk2. | US Patent US8486953 (2013) BindingDB Entry DOI: 10.7270/Q2TM78R3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human)) | BDBM98036 (US8486953, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 590 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description In vitro kinase assay using human Mnk1 and Mnk2. | US Patent US8486953 (2013) BindingDB Entry DOI: 10.7270/Q2TM78R3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
