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Compile Data Set for Download or QSAR

Found 6 hits of kd for monomerid = 31882   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor gamma [183-417]


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
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Article
PubMed
n/an/an/a 75n/an/an/a7.94



CNRS



Assay Description
Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...


J Mol Biol 302: 155-70 (2000)


Article DOI: 10.1006/jmbi.2000.4032
BindingDB Entry DOI: 10.7270/Q2BR8QHR
More data for this
Ligand-Target Pair
Retinoic acid receptor beta [200-419]


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 531n/an/an/a7.94



CNRS



Assay Description
Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...


J Mol Biol 302: 155-70 (2000)


Article DOI: 10.1006/jmbi.2000.4032
BindingDB Entry DOI: 10.7270/Q2BR8QHR
More data for this
Ligand-Target Pair
Retinoic acid receptor gamma


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
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Article
PubMed
n/an/an/a 816n/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assay


J Med Chem 39: 2411-21 (1996)


Article DOI: 10.1021/jm9502293
BindingDB Entry DOI: 10.7270/Q2MS3RVK
More data for this
Ligand-Target Pair
Retinoic acid receptor beta


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
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Article
PubMed
n/an/an/a 4.10E+3n/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Apparent binding constant for Retinoic acid receptor beta in HeLa cellGAL-4 transactivation assay


J Med Chem 39: 2411-21 (1996)


Article DOI: 10.1021/jm9502293
BindingDB Entry DOI: 10.7270/Q2MS3RVK
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
PDB
MMDB

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Article
PubMed
n/an/an/a 7.50E+3n/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Apparent binding constant against Retinoic acid receptor alpha in HeLa cell GAl-4 transactivation assay


J Med Chem 39: 2411-21 (1996)


Article DOI: 10.1021/jm9502293
BindingDB Entry DOI: 10.7270/Q2MS3RVK
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha [200-419]


(Homo sapiens (Human))
BDBM31882
PNG
(BMS184394-R | CHEMBL80992)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)[C@H](O)c1ccc2cc(ccc2c1)C(O)=O |r|
Show InChI InChI=1S/C26H28O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15,23,27H,11-12H2,1-4H3,(H,28,29)/t23-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.60E+4n/an/an/a7.94



CNRS



Assay Description
Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...


J Mol Biol 302: 155-70 (2000)


Article DOI: 10.1006/jmbi.2000.4032
BindingDB Entry DOI: 10.7270/Q2BR8QHR
More data for this
Ligand-Target Pair