BindingDB PrimarySearch

Found 5 hits of kd for monomerid = 50030474
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to PPARg (unknown origin) by SPR assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01555 BindingDB Entry DOI: 10.7270/Q20V8HGR
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars		n/a	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116877 BindingDB Entry DOI: 10.7270/Q2GB282C
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50030474 (Avandamet \| Avandaryl \| Avandia \| BRL-49653 \| CHEB...) Show SMILES CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a
Xiamen University Curated by ChEMBL					Assay Description Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance method				Bioorg Med Chem Lett 27: 1055-1061 (2017) Article DOI: 10.1016/j.bmcl.2016.12.058 BindingDB Entry DOI: 10.7270/Q2348NMW
Xiamen University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)