Found 4 hits of kd for monomerid = 50143314 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Homo sapiens (Human)) | BDBM50143314
((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description
Binding affinity to alpha4beta2 nACh receptor (unknown origin) expressed in Xenopus oocytes |
Eur J Med Chem 108: 392-405 (2016)
Article DOI: 10.1016/j.ejmech.2015.11.045
BindingDB Entry DOI: 10.7270/Q2ZS2ZCH |
More data for this
Ligand-Target Pair | |
Acetylcholine-binding protein
(Lymnaea stagnalis) | BDBM50143314
((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.0835 | n/a | n/a | n/a | 7.4 | 25 |
Beactica AB
| Assay Description
Interaction assay using AChBP. |
Biochemistry 49: 8143-54 (2010)
Article DOI: 10.1021/bi1006354
BindingDB Entry DOI: 10.7270/Q2TB15HP |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Homo sapiens (Human)) | BDBM50143314
((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano
Curated by ChEMBL
| Assay Description
Binding affinity to alpha3beta4 nACh receptor (unknown origin) expressed in Xenopus oocytes |
Eur J Med Chem 108: 392-405 (2016)
Article DOI: 10.1016/j.ejmech.2015.11.045
BindingDB Entry DOI: 10.7270/Q2ZS2ZCH |
More data for this
Ligand-Target Pair | |
Acetylcholine-binding protein
(Lymnaea stagnalis) | BDBM50143314
((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...)Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.67 | n/a | n/a | n/a | 7.4 | 25 |
Beactica AB
| Assay Description
Interaction assay using AChBP. |
Biochemistry 49: 8143-54 (2010)
Article DOI: 10.1021/bi1006354
BindingDB Entry DOI: 10.7270/Q2TB15HP |
More data for this
Ligand-Target Pair | |
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