Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50293756 (2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of... | Biochemistry 49: 8350-8 (2010) Article DOI: 10.1021/bi1005283 BindingDB Entry DOI: 10.7270/Q22V2DQ0 | |||||||||||
More data for this Ligand-Target Pair |