Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 810 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | 7.0 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair |