Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 11.6 | n/a | n/a | n/a | n/a | n/a |
University of Catania Curated by ChEMBL | Assay Description Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 5 uM BNIT | J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a |
University of Catania Curated by ChEMBL | Assay Description Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 1 uM BNIT | J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 38.2 | n/a | n/a | n/a | n/a | n/a |
George Washington University Medical Center Curated by ChEMBL | Assay Description Binding affinity against MCF cells in the membrane preparation using radioligand binding assay. | J Med Chem 37: 1737-9 (1994) BindingDB Entry DOI: 10.7270/Q2VX0FJ7 | |||||||||||
More data for this Ligand-Target Pair |