Compile Data Set for Download or QSAR

Found 8 hits of ki for monomerid = 108118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human aPC was determined by the method described in [0092]-[0098] using human activated protein C from Enzyme Research Laboratories at ...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human FXIa was determined by the method described in [0092]-[0098] using activated human Factor XI from Enzyme Research Laboratories at...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human FXa was determined by the method described in [0092]-[0098] using activated human Factor X from Enzyme Research Laboratories at 5...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Transcription initiation factor IIA subunit 1 (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human C1s was determined by the method described in [0092]-[0098] using native human activated C1s complement component from Calbioche...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM108118 (US8598206, Table 6, 1) Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCCn2cnnn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C30H42N10O4S/c31-28(32)25-11-8-23(9-12-25)19-34-29(41)26(13-10-22-14-16-33-17-15-22)36-30(42)27(7-4-18-40-21-35-38-39-40)37-45(43,44)20-24-5-2-1-3-6-24/h1-3,5-6,8-9,11-12,21-22,26-27,33,37H,4,7,10,13-20H2,(H3,31,32)(H,34,41)(H,36,42)/t26-,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition of human t-PA was determined by the method described in [0092]-[0098] using recombinant human tissue-type plasminogen activator (Actilyse&...				US Patent US8598206 (2013) BindingDB Entry DOI: 10.7270/Q25T3J5F
					More data for this Ligand-Target Pair