Compile Data Set for Download or QSAR

Found 5 hits of ki for monomerid = 14384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14384 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1 Show InChI InChI=1S/C29H32F3N5O3/c1-28(2,39-16-18-8-11-20(12-9-18)29(30,31)32)27-35-24-25(33)34-17-37(26(24)36-27)15-19-10-13-22(38-3)23(14-19)40-21-6-4-5-7-21/h8-14,17,21H,4-7,15-16,33H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14384 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1 Show InChI InChI=1S/C29H32F3N5O3/c1-28(2,39-16-18-8-11-20(12-9-18)29(30,31)32)27-35-24-25(33)34-17-37(26(24)36-27)15-19-10-13-22(38-3)23(14-19)40-21-6-4-5-7-21/h8-14,17,21H,4-7,15-16,33H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14384 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1 Show InChI InChI=1S/C29H32F3N5O3/c1-28(2,39-16-18-8-11-20(12-9-18)29(30,31)32)27-35-24-25(33)34-17-37(26(24)36-27)15-19-10-13-22(38-3)23(14-19)40-21-6-4-5-7-21/h8-14,17,21H,4-7,15-16,33H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM14384 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1 Show InChI InChI=1S/C29H32F3N5O3/c1-28(2,39-16-18-8-11-20(12-9-18)29(30,31)32)27-35-24-25(33)34-17-37(26(24)36-27)15-19-10-13-22(38-3)23(14-19)40-21-6-4-5-7-21/h8-14,17,21H,4-7,15-16,33H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	309	-36.8	n/a	n/a	n/a	n/a	n/a	8.0	22
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14384 (3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...) Show SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1 Show InChI InChI=1S/C29H32F3N5O3/c1-28(2,39-16-18-8-11-20(12-9-18)29(30,31)32)27-35-24-25(33)34-17-37(26(24)36-27)15-19-10-13-22(38-3)23(14-19)40-21-6-4-5-7-21/h8-14,17,21H,4-7,15-16,33H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP					Assay Description PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...				J Med Chem 48: 1237-43 (2005) Article DOI: 10.1021/jm030603w BindingDB Entry DOI: 10.7270/Q2GT5KF0
					More data for this Ligand-Target Pair