Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 198747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	-50.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.70	-50.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	89	-43.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	690	-38.1	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair