BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 207305   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha [Q431L,Q432E,D433V,Q434L,V435F,V436Q,K437G,E438P]/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))		BDBM207305
PNG
(US9260439, 489)
Show SMILES C[C@H]1COCCN1c1nc2N(CCc2c(n1)-c1cnc(N)nc1)[C@@]1(C)CCN(C1)C(=O)C(F)(F)CN |r|
Show InChI InChI=1S/C23H31F2N9O2/c1-14-11-36-8-7-33(14)21-30-17(15-9-28-20(27)29-10-15)16-3-5-34(18(16)31-21)22(2)4-6-32(13-22)19(35)23(24,25)12-26/h9-10,14H,3-8,11-13,26H2,1-2H3,(H2,27,28,29)/t14-,22-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.0180n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...

US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair