Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 232706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM232706 (US9346815, 252 | US9604984, Example 252) Show SMILES CN1C[C@H]2C[C@@H]1CN2C(=O)Cn1cc(NC(=O)c2c(N)nn3cccnc23)c(n1)-c1cc(Cl)ccc1OC(F)F |r| Show InChI InChI=1S/C25H24ClF2N9O3/c1-34-9-15-8-14(34)10-36(15)19(38)12-35-11-17(21(32-35)16-7-13(26)3-4-18(16)40-25(27)28)31-24(39)20-22(29)33-37-6-2-5-30-23(20)37/h2-7,11,14-15,25H,8-10,12H2,1H3,(H2,29,33)(H,31,39)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.150	-55.5	n/a	n/a	n/a	n/a	n/a	7.2	22
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US9346815 (2016) BindingDB Entry DOI: 10.7270/Q2NS0SRT
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM232706 (US9346815, 252 | US9604984, Example 252) Show SMILES CN1C[C@H]2C[C@@H]1CN2C(=O)Cn1cc(NC(=O)c2c(N)nn3cccnc23)c(n1)-c1cc(Cl)ccc1OC(F)F |r| Show InChI InChI=1S/C25H24ClF2N9O3/c1-34-9-15-8-14(34)10-36(15)19(38)12-35-11-17(21(32-35)16-7-13(26)3-4-18(16)40-25(27)28)31-24(39)20-22(29)33-37-6-2-5-30-23(20)37/h2-7,11,14-15,25H,8-10,12H2,1H3,(H2,29,33)(H,31,39)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US9604984 (2017) BindingDB Entry DOI: 10.7270/Q26D5W25
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM232706 (US9346815, 252 | US9604984, Example 252) Show SMILES CN1C[C@H]2C[C@@H]1CN2C(=O)Cn1cc(NC(=O)c2c(N)nn3cccnc23)c(n1)-c1cc(Cl)ccc1OC(F)F |r| Show InChI InChI=1S/C25H24ClF2N9O3/c1-34-9-15-8-14(34)10-36(15)19(38)12-35-11-17(21(32-35)16-7-13(26)3-4-18(16)40-25(27)28)31-24(39)20-22(29)33-37-6-2-5-30-23(20)37/h2-7,11,14-15,25H,8-10,12H2,1H3,(H2,29,33)(H,31,39)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US9604984 (2017) BindingDB Entry DOI: 10.7270/Q26D5W25
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM232706 (US9346815, 252 | US9604984, Example 252) Show SMILES CN1C[C@H]2C[C@@H]1CN2C(=O)Cn1cc(NC(=O)c2c(N)nn3cccnc23)c(n1)-c1cc(Cl)ccc1OC(F)F |r| Show InChI InChI=1S/C25H24ClF2N9O3/c1-34-9-15-8-14(34)10-36(15)19(38)12-35-11-17(21(32-35)16-7-13(26)3-4-18(16)40-25(27)28)31-24(39)20-22(29)33-37-6-2-5-30-23(20)37/h2-7,11,14-15,25H,8-10,12H2,1H3,(H2,29,33)(H,31,39)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.810	-51.4	n/a	n/a	n/a	n/a	n/a	7.2	22
Genentech, Inc. US Patent					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				US Patent US9346815 (2016) BindingDB Entry DOI: 10.7270/Q2NS0SRT
					More data for this Ligand-Target Pair