Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 280986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM280986 (3-[1-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...) Show SMILES CC1(N2CCC(CCC(O)=O)C2)C(=O)Nc2nc(nc(N)c12)-c1nn(Cc2ccccc2F)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClFN7O3/c1-28(36-11-10-15(13-36)6-9-21(38)39)22-24(31)32-26(33-25(22)34-27(28)40)23-18-8-7-17(29)12-20(18)37(35-23)14-16-4-2-3-5-19(16)30/h2-5,7-8,12,15H,6,9-11,13-14H2,1H3,(H,38,39)(H3,31,32,33,34,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The binding buffer was composed of 50 mM triethanolamine, pH 7.4, 3 mM MgCl2, 0.025% BSA, 2 mM dithiothreitol (DTT), 300 μM DETA/NO and 400 _...				US Patent US10428076 (2019) BindingDB Entry DOI: 10.7270/Q22N54P9
					More data for this Ligand-Target Pair
Guanylate cyclase soluble subunit alpha-1 (Homo sapiens (Human))	BDBM280986 (3-[1-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...) Show SMILES CC1(N2CCC(CCC(O)=O)C2)C(=O)Nc2nc(nc(N)c12)-c1nn(Cc2ccccc2F)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClFN7O3/c1-28(36-11-10-15(13-36)6-9-21(38)39)22-24(31)32-26(33-25(22)34-27(28)40)23-18-8-7-17(29)12-20(18)37(35-23)14-16-4-2-3-5-19(16)30/h2-5,7-8,12,15H,6,9-11,13-14H2,1H3,(H,38,39)(H3,31,32,33,34,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0740	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...				US Patent US10030027 (2018) BindingDB Entry DOI: 10.7270/Q22N549C
					More data for this Ligand-Target Pair
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM280986 (3-[1-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...) Show SMILES CC1(N2CCC(CCC(O)=O)C2)C(=O)Nc2nc(nc(N)c12)-c1nn(Cc2ccccc2F)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClFN7O3/c1-28(36-11-10-15(13-36)6-9-21(38)39)22-24(31)32-26(33-25(22)34-27(28)40)23-18-8-7-17(29)12-20(18)37(35-23)14-16-4-2-3-5-19(16)30/h2-5,7-8,12,15H,6,9-11,13-14H2,1H3,(H,38,39)(H3,31,32,33,34,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The binding buffer was composed of 50 mM triethanolamine, pH 7.4, 3 mM MgCl2, 0.025% BSA, 2 mM dithiothreitol (DTT), 300 μM DETA/NO and 400 _...				US Patent US10428076 (2019) BindingDB Entry DOI: 10.7270/Q22N54P9
					More data for this Ligand-Target Pair
Guanylate cyclase soluble subunit alpha-1 (Homo sapiens (Human))	BDBM280986 (3-[1-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...) Show SMILES CC1(N2CCC(CCC(O)=O)C2)C(=O)Nc2nc(nc(N)c12)-c1nn(Cc2ccccc2F)c2cc(Cl)ccc12 Show InChI InChI=1S/C28H27ClFN7O3/c1-28(36-11-10-15(13-36)6-9-21(38)39)22-24(31)32-26(33-25(22)34-27(28)40)23-18-8-7-17(29)12-20(18)37(35-23)14-16-4-2-3-5-19(16)30/h2-5,7-8,12,15H,6,9-11,13-14H2,1H3,(H,38,39)(H3,31,32,33,34,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.187	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...				US Patent US10030027 (2018) BindingDB Entry DOI: 10.7270/Q22N549C
					More data for this Ligand-Target Pair