Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 283337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM283337 (4'-(5-aminopyrazin-2-yl)-3'-fluoro-N-(2- hydroxyet...) Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccc(cc1S(=O)(=O)NCCO)C(F)(F)F Show InChI InChI=1S/C19H16F4N4O3S/c20-15-7-11(1-3-14(15)16-9-26-18(24)10-25-16)13-4-2-12(19(21,22)23)8-17(13)31(29,30)27-5-6-28/h1-4,7-10,27-28H,5-6H2,(H2,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9884878 (2018) BindingDB Entry DOI: 10.7270/Q2R78H8P
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM283337 (4'-(5-aminopyrazin-2-yl)-3'-fluoro-N-(2- hydroxyet...) Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccc(cc1S(=O)(=O)NCCO)C(F)(F)F Show InChI InChI=1S/C19H16F4N4O3S/c20-15-7-11(1-3-14(15)16-9-26-18(24)10-25-16)13-4-2-12(19(21,22)23)8-17(13)31(29,30)27-5-6-28/h1-4,7-10,27-28H,5-6H2,(H2,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...				US Patent US9745328 (2017) BindingDB Entry DOI: 10.7270/Q2H13446
					More data for this Ligand-Target Pair