BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 300267   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM300267
PNG
(US9593110, 18-6)
Show SMILES CCc1cc(on1)C(=O)N[C@@H](C[C@H](N)C(O)=O)Cc1ccc(cc1Cl)-c1cc(Cl)ccc1F
Show InChI InChI=1S/C23H22Cl2FN3O4/c1-2-15-11-21(33-29-15)22(30)28-16(10-20(27)23(31)32)7-13-4-3-12(8-18(13)25)17-9-14(24)5-6-19(17)26/h3-6,8-9,11,16,20H,2,7,10,27H2,1H3,(H,28,30)(H,31,32)/t16-,20+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



Theravence Biopharma R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...


US Patent US9593110 (2017)


BindingDB Entry DOI: 10.7270/Q2MC9224
More data for this
Ligand-Target Pair