Found 3 hits of ki for monomerid = 356626 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM356626
(US10214477, Example 12)Show SMILES NC(=O)C1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:12.14,wD:10.10,(10.21,3.85,;8.88,4.62,;8.88,6.16,;7.54,3.85,;7.54,2.31,;6.21,1.54,;4.87,2.31,;4.87,3.85,;6.21,4.62,;3.54,1.54,;2.21,2.31,;1.44,3.64,;.67,2.31,;-.67,1.54,;-2,2.31,;-3.33,1.54,;-3.33,,;-4.67,-.77,;-6,,;-7.34,-.77,;-8.67,,;-10,-.77,;-10,-2.31,;-8.67,-3.14,;-7.34,-2.31,;-8.67,-4.68,;-8.67,-6.22,;-10.21,-4.68,;-7.13,-4.68,;-2,-.77,;-.67,,)| Show InChI InChI=1S/C23H26F3N3O2/c24-23(25,26)17-3-1-2-14(10-17)13-31-21-9-6-16(12-28-21)19-11-20(19)29-18-7-4-15(5-8-18)22(27)30/h1-3,6,9-10,12,15,18-20,29H,4-5,7-8,11,13H2,(H2,27,30)/t15?,18?,19-,20+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics S.A.
US Patent
| Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ... |
US Patent US10214477 (2019)
BindingDB Entry DOI: 10.7270/Q2ZS2ZTB |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM356626
(US10214477, Example 12)Show SMILES NC(=O)C1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:12.14,wD:10.10,(10.21,3.85,;8.88,4.62,;8.88,6.16,;7.54,3.85,;7.54,2.31,;6.21,1.54,;4.87,2.31,;4.87,3.85,;6.21,4.62,;3.54,1.54,;2.21,2.31,;1.44,3.64,;.67,2.31,;-.67,1.54,;-2,2.31,;-3.33,1.54,;-3.33,,;-4.67,-.77,;-6,,;-7.34,-.77,;-8.67,,;-10,-.77,;-10,-2.31,;-8.67,-3.14,;-7.34,-2.31,;-8.67,-4.68,;-8.67,-6.22,;-10.21,-4.68,;-7.13,-4.68,;-2,-.77,;-.67,,)| Show InChI InChI=1S/C23H26F3N3O2/c24-23(25,26)17-3-1-2-14(10-17)13-31-21-9-6-16(12-28-21)19-11-20(19)29-18-7-4-15(5-8-18)22(27)30/h1-3,6,9-10,12,15,18-20,29H,4-5,7-8,11,13H2,(H2,27,30)/t15?,18?,19-,20+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 2.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics S.A.
US Patent
| Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ... |
US Patent US10214477 (2019)
BindingDB Entry DOI: 10.7270/Q2ZS2ZTB |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM356626
(US10214477, Example 12)Show SMILES NC(=O)C1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(OCc2cccc(c2)C(F)(F)F)nc1 |r,wU:12.14,wD:10.10,(10.21,3.85,;8.88,4.62,;8.88,6.16,;7.54,3.85,;7.54,2.31,;6.21,1.54,;4.87,2.31,;4.87,3.85,;6.21,4.62,;3.54,1.54,;2.21,2.31,;1.44,3.64,;.67,2.31,;-.67,1.54,;-2,2.31,;-3.33,1.54,;-3.33,,;-4.67,-.77,;-6,,;-7.34,-.77,;-8.67,,;-10,-.77,;-10,-2.31,;-8.67,-3.14,;-7.34,-2.31,;-8.67,-4.68,;-8.67,-6.22,;-10.21,-4.68,;-7.13,-4.68,;-2,-.77,;-.67,,)| Show InChI InChI=1S/C23H26F3N3O2/c24-23(25,26)17-3-1-2-14(10-17)13-31-21-9-6-16(12-28-21)19-11-20(19)29-18-7-4-15(5-8-18)22(27)30/h1-3,6,9-10,12,15,18-20,29H,4-5,7-8,11,13H2,(H2,27,30)/t15?,18?,19-,20+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 2.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Oryzon Genomics S.A.
US Patent
| Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ... |
US Patent US10214477 (2019)
BindingDB Entry DOI: 10.7270/Q2ZS2ZTB |
More data for this Ligand-Target Pair | |