Compile Data Set for Download or QSAR

Found 11 hits of ki for monomerid = 35734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration method				Bioorg Med Chem Lett 19: 3170-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.123 BindingDB Entry DOI: 10.7270/Q2TQ61V6
					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA5B by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 6674-80 (2013) Article DOI: 10.1016/j.bmc.2013.08.011 BindingDB Entry DOI: 10.7270/Q2V40Z44
					More data for this Ligand-Target Pair
Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	8.30	-46.1	n/a	n/a	n/a	n/a	n/a	n/a	25
Istanbul University					Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...				Bioorg Med Chem 17: 4894-9 (2009) Article DOI: 10.1016/j.bmc.2009.06.006 BindingDB Entry DOI: 10.7270/Q2RJ4GT1
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA5A by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 6674-80 (2013) Article DOI: 10.1016/j.bmc.2013.08.011 BindingDB Entry DOI: 10.7270/Q2V40Z44
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	8.60	-46.0	n/a	n/a	n/a	n/a	n/a	n/a	25
Istanbul University					Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...				Bioorg Med Chem 17: 4894-9 (2009) Article DOI: 10.1016/j.bmc.2009.06.006 BindingDB Entry DOI: 10.7270/Q2RJ4GT1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	54	-41.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Istanbul University					Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...				Bioorg Med Chem 17: 4894-9 (2009) Article DOI: 10.1016/j.bmc.2009.06.006 BindingDB Entry DOI: 10.7270/Q2RJ4GT1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration method				Bioorg Med Chem Lett 19: 3170-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.123 BindingDB Entry DOI: 10.7270/Q2TQ61V6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	75	-40.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Istanbul University					Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...				Bioorg Med Chem 17: 4894-9 (2009) Article DOI: 10.1016/j.bmc.2009.06.006 BindingDB Entry DOI: 10.7270/Q2RJ4GT1
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istanbul University Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration method				Bioorg Med Chem Lett 19: 3170-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.123 BindingDB Entry DOI: 10.7270/Q2TQ61V6
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA9 by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 6674-80 (2013) Article DOI: 10.1016/j.bmc.2013.08.011 BindingDB Entry DOI: 10.7270/Q2V40Z44
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM35734 (sulfonamide deriv., 7b) Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem	Article PubMed	212	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA12 by stopped-flow CO2 hydrase assay				Bioorg Med Chem 21: 6674-80 (2013) Article DOI: 10.1016/j.bmc.2013.08.011 BindingDB Entry DOI: 10.7270/Q2V40Z44
					More data for this Ligand-Target Pair