BindingDB PrimarySearch

Found 17 hits of ki for monomerid = 50015003
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting method				J Med Chem 58: 4242-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b00130 BindingDB Entry DOI: 10.7270/Q2ST7RKD
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from recombinant human kappa opioid receptor expressed in CHO cells				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes incubated for 1 hr by beta counting method				J Med Chem 58: 4242-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b00130 BindingDB Entry DOI: 10.7270/Q2ST7RKD
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]-U69,593 from human kappa opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting anal...				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	0.490	-53.1	n/a	n/a	n/a	n/a	n/a	7.4	25
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...				US Patent US9259422 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5DG0
The University of Bath US Patent					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	0.490	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...				US Patent US9480684 (2016) BindingDB Entry DOI: 10.7270/Q29885ZT
The University of Bath US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from human mu opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting analysis				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	0.710	-52.2	n/a	n/a	n/a	n/a	n/a	7.4	25
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...				US Patent US9259422 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5DG0
The University of Bath US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	0.710	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...				US Patent US9480684 (2016) BindingDB Entry DOI: 10.7270/Q29885ZT
The University of Bath US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]-DPDPE from human delta opioid receptor transfected in CHO cells after 60 mins by beta-plate liquid scintillation counting analys...				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	1.91	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...				US Patent US9480684 (2016) BindingDB Entry DOI: 10.7270/Q29885ZT
The University of Bath US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	1.91	-49.8	n/a	n/a	n/a	n/a	n/a	7.4	25
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...				US Patent US9259422 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5DG0
The University of Bath US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in HEK293 cell membranes incubated for 1 hr by beta counting method				J Med Chem 58: 4242-9 (2015) Article DOI: 10.1021/acs.jmedchem.5b00130 BindingDB Entry DOI: 10.7270/Q2ST7RKD
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]-N/OFQ from recombinant nociceptin opioid receptor (unknown origin) expressed in HEK cells				J Med Chem 57: 4049-57 (2014) Article DOI: 10.1021/jm401964y BindingDB Entry DOI: 10.7270/Q2NG4S62
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	43.2	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...				US Patent US9480684 (2016) BindingDB Entry DOI: 10.7270/Q29885ZT
The University of Bath US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50015003 (CHEMBL3262089 \| US9259422, 7a, R = Ph-BU127 \| US94...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	43.2	-42.0	n/a	n/a	n/a	n/a	n/a	7.4	25
The University of Bath US Patent					Assay Description As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...				US Patent US9259422 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5DG0
The University of Bath US Patent					More data for this Ligand-Target Pair