Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1 | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudate | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (CALF) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- prazosin radioligand binding at the alpha 1-adrenergic binding site of calf cerebral cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- apomorphine radioligand binding at the dopamine binding site of rat caudate | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (BOVINE) | BDBM50026971 (11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]- clonidine radioligand binding at the alpha-2 adrenergic receptor binding site of calf cerebral cortex | J Med Chem 26: 974-80 (1983) BindingDB Entry DOI: 10.7270/Q2DR2W2B | |||||||||||
More data for this Ligand-Target Pair |