Found 3 hits of ki for monomerid = 50031822 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description Competitive inhibition of human NPP1 using p-Nph-5'-TMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description Inhibition of human NPP1 using p-Nph-5'-TMP as substrate |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description Competitive inhibition of human NPP1 using ATP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this Ligand-Target Pair | |