Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50131114 (2-{6-Methyl-2-[(tetrahydro-furan-2-ylmethyl)-amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase | Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM50131114 (2-{6-Methyl-2-[(tetrahydro-furan-2-ylmethyl)-amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of Fyn protein kinase | Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50131114 (2-{6-Methyl-2-[(tetrahydro-furan-2-ylmethyl)-amino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase | Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4 | |||||||||||
More data for this Ligand-Target Pair |