Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50160720 (3-hydroxy-3-methylglutaric acid | 3-hydroxy-3-meth...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 23.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Autónoma de México Curated by ChEMBL | Assay Description Inhibitory constant against HMG-CoA reductase | Bioorg Med Chem Lett 15: 989-94 (2005) Article DOI: 10.1016/j.bmcl.2004.12.046 BindingDB Entry DOI: 10.7270/Q2BC3Z1P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |