Compile Data Set for Download or QSAR

Found 5 hits of ki for monomerid = 50194639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50194639 ((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC2CCC2)CC1 Show InChI InChI=1S/C42H49F3N4O4/c43-33-12-6-30(7-13-33)42(31-8-14-34(44)15-9-31,32-10-16-35(45)17-11-32)24-39(51)49-27-36(50)23-38(49)41(53)48-20-2-5-37(48)40(52)46-25-28-18-21-47(22-19-28)26-29-3-1-4-29/h6-17,28-29,36-38,50H,1-5,18-27H2,(H,46,52)/t36-,37-,38+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50194639 ((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC2CCC2)CC1 Show InChI InChI=1S/C42H49F3N4O4/c43-33-12-6-30(7-13-33)42(31-8-14-34(44)15-9-31,32-10-16-35(45)17-11-32)24-39(51)49-27-36(50)23-38(49)41(53)48-20-2-5-37(48)40(52)46-25-28-18-21-47(22-19-28)26-29-3-1-4-29/h6-17,28-29,36-38,50H,1-5,18-27H2,(H,46,52)/t36-,37-,38+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50194639 ((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC2CCC2)CC1 Show InChI InChI=1S/C42H49F3N4O4/c43-33-12-6-30(7-13-33)42(31-8-14-34(44)15-9-31,32-10-16-35(45)17-11-32)24-39(51)49-27-36(50)23-38(49)41(53)48-20-2-5-37(48)40(52)46-25-28-18-21-47(22-19-28)26-29-3-1-4-29/h6-17,28-29,36-38,50H,1-5,18-27H2,(H,46,52)/t36-,37-,38+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M2 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50194639 ((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC2CCC2)CC1 Show InChI InChI=1S/C42H49F3N4O4/c43-33-12-6-30(7-13-33)42(31-8-14-34(44)15-9-31,32-10-16-35(45)17-11-32)24-39(51)49-27-36(50)23-38(49)41(53)48-20-2-5-37(48)40(52)46-25-28-18-21-47(22-19-28)26-29-3-1-4-29/h6-17,28-29,36-38,50H,1-5,18-27H2,(H,46,52)/t36-,37-,38+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M1 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50194639 ((2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)N1CCC[C@@H]1C(=O)NCC1CCN(CC2CCC2)CC1 Show InChI InChI=1S/C42H49F3N4O4/c43-33-12-6-30(7-13-33)42(31-8-14-34(44)15-9-31,32-10-16-35(45)17-11-32)24-39(51)49-27-36(50)23-38(49)41(53)48-20-2-5-37(48)40(52)46-25-28-18-21-47(22-19-28)26-29-3-1-4-29/h6-17,28-29,36-38,50H,1-5,18-27H2,(H,46,52)/t36-,37-,38+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M5 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair