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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50222918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM50222918
PNG
(4'-(5-phenylamino-2H-pyrazol-3-yl)-biphenyl-2,4-di...)
Show SMILES Oc1ccc(c(O)c1)-c1ccc(cc1)-c1cc(Nc2ccccc2)[nH]n1
Show InChI InChI=1S/C21H17N3O2/c25-17-10-11-18(20(26)12-17)14-6-8-15(9-7-14)19-13-21(24-23-19)22-16-4-2-1-3-5-16/h1-13,25-26H,(H2,22,23,24)
PDB
MMDB

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Article
PubMed
1.20n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human CHK1 expressed in baculovirus/insect cell system


J Med Chem 50: 5253-6 (2007)


Article DOI: 10.1021/jm0704604
BindingDB Entry DOI: 10.7270/Q2K0754D
More data for this
Ligand-Target Pair